What benefits of Isaria fumosorosea have been cited in the scientific literature?
The strongest quantified data concern Colorado potato beetle (Leptinotarsa decemlineata) and whitefly (Bemisia tabaci). Strain CCM 8367 is reported to cause 92.6% larval mortality (LT50 = 5.0 days; LC50 = 1.03×10⁶ blastospores/mL) against L. decemlineata. When combined with the entomopathogenic nematode Steinernema feltiae, simultaneous application is reported to push larval mortality to 98.0%, cutting LT50 to 2.0 days. For B. tabaci, blastospores are reported to outperform aerial conidia in speed and concentration, and a recombinant strain targeting the whitefly TLR7 immunity gene is reported to further reduce LC50 and LT50 values versus the wild-type.
Isaria fumosorosea efficacy against Lobesia botrana (European grapevine moth) is also cited in the literature — up to 77.5% larval mortality co-applied with salicylic acid at 24°C — and against rugose spiraling whitefly on oil palm via community-scale production. A separate study reported that foliar application increased electron transport rate, transpiration, and stomatal conductance in Vitis vinifera compared to untreated controls. All findings are from peer-reviewed research and do not constitute approved label claims or regulatory endorsements.
1Potential claims from the literature
Reported to cause mortality in immature stages (last-instar larvae, pre-pupae, and pupae) of the Colorado potato beetle (Leptinotarsa decemlineata), with strain CCM 8367 causing 92.6% larval mortality (LT50 = 5.0 days) and an LC50 of 1.03×10⁶ blastospores/mL
Reported to cause mortality in whitefly (Bemisia tabaci) nymphs, with blastospores killing nymphs faster and at lower concentrations compared with aerial conidia
Reported to be effective as a biocontrol agent against rugose spiraling whitefly (RSW) on oil palm when produced via a two-step community-scale mass production strategy
Reported to achieve higher virulence against Bemisia tabaci nymphs when engineered as a recombinant strain expressing dsRNA targeting the whitefly TLR7 immunity gene, resulting in increased nymph mortality and reduced LC50 and LT50 values compared to the wild-type strain
Reported to achieve up to 98.0% mortality of Colorado potato beetle larvae when combined with the entomopathogenic nematode Steinernema feltiae, with simultaneous application yielding the shortest LT50 (2.0 days)
Reported to have its spore dispersal (both conidia and blastospores) significantly enhanced by the presence of entomopathogenic nematodes Steinernema feltiae and Heterorhabditis bacteriophora, potentially improving environmental distribution of the fungus
Reported to cause larval mortality in Lobesia botrana (European grapevine moth), with combined application with salicylic acid achieving up to 77.5% larval mortality at 24°C
Reported to increase the electron transport rate (ETR) from PSII to PSI, transpiration rate (E), and stomatal conductance (gs) in grapevine (Vitis vinifera) following foliar application, indicating higher photosynthetic activity compared to control plants
Reported to be producible via liquid culture fermentation using cottonseed flour as a nitrogen source, yielding blastospore concentrations >1×10⁹ mL⁻¹ within 3 days, with air-dried blastospores showing 61–86% viability after desiccation and storage half-lives of 9.2–13.1 months at 4°C
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