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What does the published scientific research say about Metarhizium anisopliae?

Source: PubMed and scientific literature databases

Research on Metarhizium anisopliae efficacy spans multiple pest types. Peer-reviewed studies report lethal and transgenerational effects on Oxycarenus hyalinipennis, a cotton pest, and a systematic review of 49 parasitoid–microorganism combinations found M. anisopliae compatible with 38 pairings, supporting integration into broader IPM programs. Efficacy is not universal: one study found it a poor bed bug pathogen at ambient humidity, underscoring that humidity, strain selection, and application method all affect outcomes.

Peer-reviewed research also reports Metarhizium anisopliae plant growth promotion — increased fresh weight and chlorophyll content — in Arabidopsis, tomato, and maize, attributed to its endophytic lifestyle. The literature cites additional roles in abiotic stress tolerance and soil nutrient distribution, though the authors note these secondary functions remain far less documented than M. anisopliae's primary biocontrol use.

Metarhizium anisopliae: A fungal biocontrol agent against Rhipicephalus microplus
de Fraga Sant'Ana J, Santi L, Beys-da-Silva WO· PLoS pathogens· 2026PMID 41615971
Interactions between Entomopathogenic Fungi and Insects and Prospects with Glycans
Liu D, Smagghe G, Liu TX· Journal of fungi (Basel, Switzerland)· 2023PMID 37233286
Virulence and transgenerational effects of Metarhizium anisopliae on Oxycarenus hyalinipennis
Shaukat RF, Freed S, Ahmed R et al.· Pest management science· 2023PMID 37253932
Entomopathogens and Parasitoids Allied in Biocontrol: A Systematic Review
Koller J, Sutter L, Gonthier J et al.· Pathogens (Basel, Switzerland)· 2023PMID 37513804
The entomopathogenic fungus Metarhizium anisopliae enhances Arabidopsis, tomato, and maize plant growth
González-Pérez E, Ortega-Amaro MA, Bautista E et al.· Plant physiology and biochemistry : PPB· 2022PMID 35217328
Fungal Endophytes: Beyond Herbivore Management
Bamisile BS, Dash CK, Akutse KS et al.· Frontiers in microbiology· 2018PMID 29628919
Exposure of Bed Bugs to Metarhizium anisopliae at Different Humidities
Ulrich KR, Feldlaufer MF, Kramer M et al.· Journal of economic entomology· 2014PMID 26470085
Biological control of ticks
Samish M, Ginsberg H, Glazer I· Parasitology· 2004PMID 15938520

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